Adenosine Receptors in Neurology and Psychiatry: 119 by Akihisa Mori

By Akihisa Mori

This well-established foreign sequence examines significant components of uncomplicated and scientific examine inside neuroscience, in addition to rising and promising subfields. This quantity concentrates on adenosine receptor technology, supplying insights important for genuine drug discovery/development in neurology and psychiatry areas.

  • Expertise of contributors
  • Subject together with functional drug improvement from uncomplicated technology, as translational study taste
  • Structure of contents targeting CNS components for illnesses (neurology and psychiatry)

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Ackley, M. , Cass, C. , Young, J. , & Baldwin, S. A. (2006). Nucleoside transporters: From scavengers to novel therapeutic targets. Trends in Pharmacological Sciences, 27, 416–425. Kirsch, G. , & Brown, A. M. (1990). Coupling of ATPsensitive K + channels to A1 receptors by G proteins in rat ventricular myocytes. The American Journal of Physiology, 259, H820–H826. , & Millhorn, D. E. (1999). Stimulation of expression for the adenosine A2A receptor gene by hypoxia in PC12 cells. A potential role in cell protection.

Modification of adenosine A1 and A2A receptor density in the hippocampus of streptozotocin-induced diabetic rats. Neurochemistry International, 48, 144–150. Dumont, J. , & Maenhaut, C. (2001). Crosstalk and specificity in signalling. Are we crosstalking ourselves into general confusion? Cellular Signalling, 13, 457–463. Dunwiddie, T. , & Fredholm, B. B. (1997). Adenosine neuromodulation. In K. A. Jacobson, & M. F. ), Purinergic approaches in experimental therapeutics (pp. 359–382). New York, NY: Wiley-Liss.

Neurobiology of Aging, 30, 1877–1884. Canas, P. , Porciuncula, L. , Cunha, G. , Silva, C. , Machado, N. , Oliveira, J. , et al. (2009). Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway. The Journal of Neuroscience, 29, 14741–14751. , Canela, E. , et al. (2007). The neuronal Ca(2+)-binding protein 2 (NECAB2) interacts with the adenosine A(2A) receptor and modulates the cell surface expression and function of the receptor.

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