Amino Acids as Chemical Transmitters by Victoria Chan-Palay (auth.), Frode Fonnum (eds.)

By Victoria Chan-Palay (auth.), Frode Fonnum (eds.)

This quantity represents the complaints of a NATO complicated learn Institute on Amino Acids as Chemical Transmitters, which took ~lace at Spatind lodge in Norway, August 14-21, 1977. The assembly is said to 2 prior conferences on metabolic compart­ mentation within the mind. the 1st of those conferences happened at Rockefeller origin, Bellagio, Italy, July 11-16, 1971 and the complaints, Metabolic Compartmentation in mind, have been edited via R. Balazs and J. E. Cremer and released through Macmillan in 1973. the second one assembly was once a sophisticated examine Institute on Metabolic Com­ partmentation and Neurotransmission Relation to mind constitution and serve as, which used to be held in Oxford, September 1-8, 1974. The lawsuits have been edited by means of S. Berl, D. D. Clarke and D. Schneider and released as quantity 6 of the NATO ASI existence technological know-how sequence through Plenum Press. the thing of the current assembly used to be to study and talk about the current prestige of amino acids as chemical transmitters. numerous concerns resembling electrophysiological reaction, localization, synthe­ sis, unencumber and receptor binding of transmitter applicants have been mentioned. the prospective morphological correlates to those func­ tions have been additionally reviewed. in the course of the assembly 24 prime papers got. furthermore, numerous of the members awarded very important new findings throughout the dialogue. a few of these were integrated as brief studies. the most monetary aid used to be bought from NATO, clinical Affairs Division.

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1976, An autoradiographic identi~ication o~ Purkinje axon terminals in the cat, J. , 5:157-169. , 1976, Acetylcholinesterase activity o~ synaptic structures :i:n the s:pinal trigeminal nucleus, J. , 5: 551-:563. ULTRASTRUCTURAL ANALYSIS OFAXO-DENDRITIC INITIAL COLLATERAL TERMINALS OF A FELINE SPINOCERVICAL TRACT NEURONE, STAINED INTRACELLULARLY WITH HORSERADISH PEROXIDASE Jonas Rastad Department of Anatomy, University of Uppsala Box 571, S-751 23 Uppsala, Sweden The introduction of intracellular staining methods in neurobiology has provided possibilities for extensive light and electron microscopical studies of single neurones.

I). The total length of all traced collateral branches amounted to about 10900 ~m, and they were situated in a rostro-caudal domain of the 42 J. RASTAD FIGURE 2: Light micrograph of stained collateral boutons (double arrow). The terminals are aligned along a profile ultrastructurally identified as a dendrite. The terminals are mainly boutons of passage, connected by thin terminal axons (single arrow). 700x. spinal cord of about 1000 ~m. The collateral showed, by light microscopy, a total of 274 terminal enlargements.

Mitochondria are the major sites of catabolism of H-5HT and therefore are commonly labeled in auto- 25 A STUDY OF SEROTONIN NEURONS TABLE 4. INTRACELLULAR ORGANELLES FOR THE SEQUESTRATION OF 5HT NEURONS OF MAMMALIAN CNS. Method Functional Mechanism tFluores. endogenous 5HT storage synthesis transport Immunocytochem. tryptophan h;y:drox;y:lase synthesis transport (LM) (EM) Cell Body Dendrites reticular (non-granular) Axons -- + + (rf. Joh et al. , microtubules microtubules 1975,raphe neurons) endoplasmic ret.

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